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Culture - duodenal tissue
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Culture - duodenal tissue

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Duodenal tissue culture

A duodenal tissue culture is a laboratory exam to check a piece of tissue from the first part of the small intestine (duodenum). The test is to look for organisms that cause infection.

I Would Like to Learn About:

  • How the Test is Performed

    A piece of tissue from the first part of the small intestine is taken during an upper endoscopy (esophagogastroduodenoscopy).

    The sample is then sent to a lab, and placed in a special dish (culture media) that allows bacteria or viruses to grow. The sample is looked at under a microscope regularly to see if any organisms are growing.

    Organisms that grow on the culture are identified.

  • This is a test done in a lab. The sample is collected during an upper endoscopy and biopsy procedure (esophagogastroduodenoscopy). Ask your health care provider how to prepare for this procedure.

  • Why the Test is Performed

    A culture of duodenal tissue is done to check for bacteria or viruses that may lead to certain illnesses and conditions.

  • Normal Results

    No harmful bacteria or viruses are found.

  • What Abnormal Results Mean

    An abnormal finding means that harmful bacteria or a virus has been found in the tissue sample. Bacteria may include:

    • Campylobacter
    • Helicobacter pylori
    • Salmonella
  • Considerations

    Other tests are very often done to look for infection-causing organisms in duodenal tissue. These tests include the urease test (for example, the Clotest) and histology (looking at the tissue under a microscope).

    Routine culture for H. pylori is not currently recommended.

Related Information

     

References

DuPont HL. Approach to the patient with suspected enteric infection. In: Goldman L, Schafer AI, eds. Cecil Medicine. 24th ed. Philadelphia, PA: Saunders Elsevier; 2011:chap 291.

Semrad CE. Approach to the patient with diarrhea and malabsorption. In: Goldman L, Schafer AI, eds. Cecil Medicine. 24th ed. Philadelphia, PA: Saunders Elsevier; 2011:chap 142.

Giannella RA. Infectious enteritis and proctocolitis and bacterial food poisoning. In: Feldman M, Friedman LS, Brandt LJ, eds. Sleisenger & Fordtran's Gastrointestinal and Liver Disease. 9th ed. Philadelphia, PA: Saunders Elsevier; 2010:chap 107.

Croft AC, Woods GL. Specimen collection and handling for diagnosis of infectious diseases. In: McPherson RA, Pincus MR, eds. Henry's Clinical Diagnosis and Management by Laboratory Methods. 22nd ed. Philadelphia, PA: Saunders Elsevier; 2011:chap 63.

Salwen MJ, Siddiqi HA, Gress FG, Bowne WB. Laboratory diagnosis of gastrointestinal and pancreatic disorders. In: McPherson RA, Pincus MR, eds. Henry's Clinical Diagnosis and Management by Laboratory Methods. 22nd ed. Philadelphia, PA: Saunders Elsevier; 2011:chap 22.

Fritsche R, Selvarangan R. Medical parasitology. In: McPherson RA, Pincus MR, eds. Henry's Clinical Diagnosis and Management by Laboratory Methods. 22nd ed. Philadelphia, PA: Saunders Elsevier; 2011:chap 62.

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Review Date: 5/15/2014  

Reviewed By: Jenifer K. Lehrer, MD, Department of Gastroenterology, Frankford-Torresdale Hospital, Aria Health System, Philadelphia, PA. Review provided by VeriMed Healthcare Network. Also reviewed by David Zieve, MD, MHA, Isla Ogilvie, PhD, and the A.D.A.M. Editorial team.

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