/SiteAssets/Images/FMOLHSBlankBanner.png

Health Information

Parathyroid hormone-related protein blood test
Bookmarks

Parathyroid hormone-related protein blood test

Print-Friendly  

PTHrp; PTH-related peptide

The parathyroid hormone-related protein (PTH-RP) test measures the level of a hormone in the blood, called parathyroid hormone-related protein.

I Would Like to Learn About:

  • How the Test is Performed

    A blood sample is needed.

  • How to Prepare for the Test

    No special preparation is necessary.

  • How the Test will Feel

    When the needle is inserted to draw blood, some people feel moderate pain. Others feel only a prick or stinging sensation. Afterward, there may be some throbbing or slight bruising. This soon goes away.

  • Why the Test is Performed

    This test is done to find out whether a high blood calcium level is caused by an increase in PTH-related protein.

  • Normal Results

    No detectable (or minimal) PTH-like protein is normal.

    Women who are breastfeeding may have detectable PTH-related protein values.

    The examples above are common measurements for results for these tests. Normal value ranges may vary slightly among different laboratories. Some labs use different measurements or may test different specimens. Talk to your doctor about the meaning of your specific test results.

  • What Abnormal Results Mean

    Increased levels of PTH-related protein with high blood calcium level is usually caused by cancer.

    PTH-related protein can be produced by many different kinds of cancers, including those of the lung, breast, head, neck, bladder, and ovaries, as well as leukemia and lymphoma. A high level of PTH-related protein is the cause of a high calcium level in about two-thirds of cancer patients. This condition is called humoral hypercalcemia of malignancy (HHM).

  • Risks

    Veins and arteries vary in size from one patient to another and from one side of the body to the other. Obtaining a blood sample from some people may be more difficult than from others.

    Other risks associated with having blood drawn are slight but may include:

    • Excessive bleeding
    • Fainting or feeling light-headed
    • Hematoma (blood accumulating under the skin)
    • Infection (a slight risk any time the skin is broken)

Related Information

  Parathyroid hormon...Calcium - ionized...    

References

Bringhurst FR, Demay MB, Kronenberg HM. Hormones and disorders of mineral metabolism. Melmed S, Polonsky KS, Larsen PR, Kronenberg HM, eds. Williams Textbook of Endocrinology. 12th ed. Philadelphia, Pa: Elsevier Saunders; 2011:chap 28.

Wysolmerski JJ, Insogna KL. The parathyroid glands, hypercalcemia, and hypocalcemia. In: Goldman L, Schafer AI, eds. Goldman's Cecil Medicine. 24th ed. Philadelphia, Pa: Elsevier Saunders; 2011:chap 253.

BACK TO TOP 

Review Date: 11/7/2013  

Reviewed By: Brent Wisse, MD, Associate Professor of Medicine, Division of Metabolism, Endocrinology & Nutrition, University of Washington School of Medicine. Also reviewed by David Zieve, MD, MHA, Bethanne Black, and the A.D.A.M. Editorial team.

The information provided herein should not be used during any medical emergency or for the diagnosis or treatment of any medical condition. A licensed medical professional should be consulted for diagnosis and treatment of any and all medical conditions. Call 911 for all medical emergencies. Links to other sites are provided for information only -- they do not constitute endorsements of those other sites. © 1997- A.D.A.M., Inc. Any duplication or distribution of the information contained herein is strictly prohibited.

adam.com

 
A.D.A.M. content is best viewed in IE9 or above, Fire Fox and Google Chrome browser.