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Post-splenectomy syndrome
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Post-splenectomy syndrome

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Splenectomy - post-surgery syndrome

Post-splenectomy syndrome can occur after surgery to remove the spleen. It consists of a group of symptoms and signs such as:

These include:

  • Destruction of red blood cells
  • Increased risk of getting severe infections, from bacteria such as Streptococcus pneumoniae and Neisseria meningitidis
  • Thrombocytosis (increased platelet count, which can cause blood clots)

I Would Like to Learn About:

  • Possible Complications

    Possible long-term medical problems include:

    • Hardening of the arteries (atherosclerosis)
    • Pulmonary hypertension (a disease affecting the blood vessels in your lungs)

Related Information

  Spleen removalPlatelet countBlood clotsHemolysis    

References

Connell NT, Shurin SB, Schiffman FJ. The spleen and its disorders. In: Hoffman R, Benz EJ Jr, Silberstein LE, Heslop HE, Weitz JI, eds. Hematology: Basic Principles and Practice. 6th ed. Philadelphia, Pa: Saunders Elsevier; 2012:chap 162.

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Review Date: 3/3/2013  

Reviewed By: Yi-Bin Chen, MD, Leukemia/Bone Marrow Transplant Program, Massachusetts General Hospital. Also reviewed by A.D.A.M. Health Solutions, Ebix, Inc., Editorial Team: David Zieve, MD, MHA, Bethanne Black, Stephanie Slon, and Nissi Wang.

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